来源:bwin必赢国际 发布时间:2020-04-27
一、基本情况介绍
杨洪鸣,女,正高级实验师,执业药师。
二、教学工作
承担实验教学工作。
三、科研工作
1、主持或参加科研项目(限5项以内)
[1] SpG亲和肽靶向抗体Fc位点的共价偶联标记研究及临床免疫学检验应用,国家自然科学基金面上项目,81971998,2020-01至2023-12,55万元,在研,主持
[2] ZZ-His亲和肽介导IgG抗体在聚苯乙烯载体表面的立体定向固定,国家自然科学基金青年基金,81201346,2013-01至2015-12,24万元,结题,主持
[3] 产学合作协同育人背景下药学实验教学中心运行体制改革实践,教育部产学合作协同育人项目,22060542163606,2022-07至2023-07,在研,主持
2、代表性论著(限5项以内)
[1] XK Zhang#, HM Yang#, MR Li, XY Gao, XW Sun, XF Sun, JB Tang*, Development of site-specific antibody-conjugated immunoliposomes for sensitive detection of disease biomarkers, Nanoscale, 2021, 13: 17648-17654
[2] XT Yu#, XY Fu#, XY Gao, XK Zhang, SJ Liang, HM Yang*, JB Tang*, Fc-specific and covalent conjugation of a fluorescent protein to a native antibody through a photoconjugation strategy for fabrication of a novel photostable fluorescent antibody, Anal Bioanal Chem, 2021, 413(3): 945-953.
[3] HM Yang, RM Bao, CM Yu, WF Zhang, JB Tang*, Fc-specific biotinylation of antibody using an engineered photoactivatable Z–Biotin and its biosensing application, Anal Chim Acta, 2017, 949:76-82.
[4] HM Yang, RM Bao, YZ Cheng, JB Tang*, Site-specific covalent attachment of an engineered Z-domain onto a solid matrix: an efficient platform for 3D IgG immobilization, Anal Chim Acta, 2015, 872:1-6. (Cover article)
[5] HM Yang, SJ Liang, JB Tang*, Y Chen, YZ Cheng, Immobilization of unraveled immunoglobulin G using well-oriented ZZ-His protein on functionalized microtiter-plate for sensitive immunoassay, Anal Biochem, 2013, 432:134-148.
3、授权发明专利(限5项以内)
[1] 杨洪鸣,唐金宝,鲍如梦. 一种精准Fc位点共价偶联标记的生物素化抗体,2020-04,中国,ZL201600897782.2.