来源:bwin必赢国际 发布时间:2022-09-02
一、基本情况介绍
吴伟,女,中共党员,讲师,理学博士。2016年获青岛大学医学学士学位;2019年获中国药科大学理学硕士学位;2022年获中国药科大学理学博士学位,导师:杭太俊教授。研究领域:体内药物分析、中药药物代谢动力学。电子邮箱:wuwei@wfmc.edu.cn。
二、教学工作
承担研究生《药学英语》及《现代药物分析选论》教学工作。
三、科研工作
1、主持或参加科研项目(限5项以内)
[1] 基于SLC家族转运蛋白研究雷公藤甲素治疗类风湿关节炎的毒效调控机制,国家自然科学基金面上项目,81673684,2017-01至2020-12, 57万元,已结题,参加
[2] 基于代谢酶调控的当归补血汤在吉西他滨治疗非小细胞肺癌中的减毒增效机制研究,国家自然科学基金面上项目,81673678,2017-01至2020-12,56万元,已结题,参加
[3] 类固醇激素动态谱结合芯片技术研究雷公藤甲素生殖毒和抗炎免疫的毒-效相关性,青年科学基金项目,81303301,2014-01至2016-12, 23万元,已结题,参加
2、代表性论著(限5项以内)
[1] Wei Wu, Rui Cheng, Hamza Boucetta, Lei Xu, JingRu Pan, Min Song, Yuting Lu*, Taijun Hang*. Differences in Multicomponent Pharmacokinetics, Tissue Distribution, and Excretion of Tripterygium Glycosides Tablets in Normal and Adriamycin-Induced Nephrotic Syndrome Rat Models and Correlations With Efficacy and Hepatotoxicity, Frontiers in Pharmacology, 2022, 13: 910923.
[2] Wei Wu, Rui Cheng, Zhenzhou Jiang, Luyong Zhang, Xin Huang*. UPLC-MS/MS method for the simultaneous quantification of pravastatin, fexofenadine, rosuvastatin, and methotrexate in a hepatic uptake model and its application to the possible drug-drug interaction study of triptolide, Biomedical Chromatography, 2021, 35: e5093.
[3] Hamza Boucetta#, Wei Wu# (共同一作), Tao Hong, Rui Cheng, Jing Jiang, Chengxi Liu, Min Song, Taijun Hang*.Pharmacovigilance of Herb-Drug Interactions: A Pharmacokinetic Study on the Combined Administration of Tripterygium Glycosides Tablets and Leflunomide Tablets in Rats by LC-MS/MS, Pharmaceuticals (Basel), 2022, 15: 991.
[4] Lingyan Xu, Wei Wu# (共同一作), Rui Cheng, Lixin Sun, Zhenzhou Jiang, Luyong Zhang, Zunjian Zhang , Yuwen Su, Xin Huang*. Toxic effects of triptolide on adrenal steroidogenesis in H295R cells and female rats[J]. Journal of Biochemical and Molecular Toxicology, 2019, 33: e22394.
[5] 吴伟,沈青青,徐玲燕,杜娟,江振洲,张陆勇,黄鑫*. 炎症对药物转运体的影响研究进展[J].中国药理学与毒理学杂志,2018,32(05):407-414.