一、基本情况介绍

王琳琳，女，讲师，博士。

二、教学工作

承担《药理学》教学工作。

三、科研工作

1、代表性论著（限5项以内）

[1] Wang Linlin^#, Liu Jianghong^#, Wang Qian, Jiang Hailun, Zhang Yajie, Li Zhuorong*, Liu Rui*. “MicroRNA-200a-3p mediates neuroprotection in Alzheimer-related deficits and attenuates amyloid-beta overproduction and tau hyperphosphorylation via co-regulating BACE1 and PRKACB, Frontiers in Pharmacology, 2019, 10:806. 

[2] Wang Linlin^#, Fang Jiansong ^#, Jiang Hailun, Wang Qian, Xue Situ, Li Zhuorong*, Liu Rui*. 7-pyrrolidinethoxy-4' -methoxyisoflavone, a potential histamine H3 receptor antagonist, ameliorates amyloid β-mediated injury in Alzheimer's disease models” Frontiers in Neuroscience, 2019,13:334.

[3] Wang Linlin, Min Li, Guo Qingdong, Zhang Junxia, Jiang Hailun, Shao Shuai, Xing Jianguo, Yin linlin, Liu Jianghong, Liu Rui*, Guo Shuilong*. Profiling microRNA from Brain by Microarray in a Transgenic Mouse Model of Alzheimer’s Disease, BioMed Research International, 2017. doi:10.1155/2017/8030369.

[4] Zhang Junxia, Xing Jianguo, Wang Linlin, Jiang Hailun, Guo Shuilong*, Liu Rui*. Luteolin Inhibits Fibrillary β-Amyloid_1–40-Induced Inflammation in a Human Blood-Brain Barrier Model by Suppressing the p38 MAPK-Mediated NF-κB Signaling Pathways, Molecules, 2017, 22:334.

[5] Liu Qingshan., Jiang Hailun., Wang Yu., Wang Linlin, Zhang Junxia, He Chenghui, Shao Shuai, Zhang Tiantai, Xing Jianguo, Liu Rui*. Total flavonoid extract from Dracoephalum Moldavia L. attenuates β-amyloid-induced toxicity through anti-amyloidgenesic and neurotrophic pathways, Life Sciences, 2017, 193:214-225.